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John L Nitiss Selected Research

DNA Topoisomerases

10/2021Topoisomerase Assays.
11/2019Kinetic Study of DNA Topoisomerases by Supercoiling-Dependent Fluorescence Quenching.
6/2012Topoisomerase assays.
10/2002DNA topoisomerases in cancer chemotherapy: using enzymes to generate selective DNA damage.

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John L Nitiss Research Topics

Disease

20Neoplasms (Cancer)
12/2023 - 01/2002
6Genomic Instability
01/2022 - 11/2016
4Hypersensitivity (Allergy)
12/2023 - 06/2006
2Small Cell Lung Carcinoma (Small Cell Lung Cancer)
08/2003 - 06/2002
1Smallpox (Variola)
11/2019
1Neurodegenerative Diseases (Neurodegenerative Disease)
11/2016
1Immune System Diseases (Immune Disorders)
11/2016
1Cardiotoxicity
09/2014
1Ataxia Telangiectasia (Louis Bar Syndrome)
06/2014
1Spinocerebellar Ataxias (Spinocerebellar Ataxia)
06/2014
1Leukemia
12/2012
1Carcinogenesis
05/2009
1Genetic Translocation (Chromosomal Translocation)
06/2006
1Glioblastoma (Glioblastoma Multiforme)
07/2005
1DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
06/2004

Drug/Important Bio-Agent (IBA)

13Type II DNA Topoisomerases (Topoisomerase II)IBA
11/2023 - 01/2002
10EnzymesIBA
12/2023 - 06/2002
6DNA (Deoxyribonucleic Acid)IBA
11/2023 - 05/2009
5Etoposide (VP 16)FDA LinkGeneric
12/2023 - 10/2002
4Adenosine Triphosphatases (ATPase)IBA
12/2023 - 06/2002
4PoisonsIBA
11/2023 - 12/2012
4DNA TopoisomerasesIBA
10/2021 - 10/2002
3Type I DNA Topoisomerases (Topoisomerase I)IBA
11/2019 - 10/2002
2beta-cyclodextrin tetradecasulfate (CTDS)IBA
12/2023 - 06/2023
2Doxorubicin (Adriamycin)FDA LinkGeneric
09/2014 - 10/2002
2Phosphotransferases (Kinase)IBA
06/2014 - 12/2012
2Intercalating AgentsIBA
10/2008 - 06/2006
2Antineoplastic Agents (Antineoplastics)IBA
06/2006 - 12/2005
2Dexrazoxane (Zinecard)FDA LinkGeneric
08/2003 - 06/2002
1A-Form DNA (A-DNA)IBA
11/2023
1Mutant Proteins (Protein, Mutant)IBA
01/2022
1FluoroquinolonesIBA
10/2019
1QuinolonesIBA
01/2019
1vosaroxinIBA
01/2019
1Ciprofloxacin (Cipro)FDA LinkGeneric
01/2019
1ChromatinIBA
11/2016
1AnthracyclinesIBA
09/2014
1Mitochondrial DNA (mtDNA)IBA
09/2014
14- amino- 5- fluoro- 3- (5- (4- methylpiperazin- 1- yl)- 1H- benzimidazol- 2- yl)quinolin- 2(1H)- oneIBA
12/2012
1CamptothecinIBA
07/2005
1ST 1481 (Gimatecan)IBA
07/2005
1tafluposideIBA
08/2003
1Protein Isoforms (Isoforms)IBA
08/2003
1Irinotecan (Camptosar)FDA LinkGeneric
10/2002
1Topotecan (Hycamtin)FDA LinkGeneric
10/2002
1Adenosine Triphosphate (ATP)IBA
06/2002

Therapy/Procedure

4Drug Therapy (Chemotherapy)
05/2009 - 01/2002
1Therapeutics
12/2023